The proposed mechanism of Firapy (WS™ Far-infrared Therapy Unit) in PAOD
Reference
Biological effect of far-infrared therapy on increasing skin microcirculation in rats. Photodermatol Photoimmunol Photomed. 2006 Apr;22(2):78-86.
Far infrared therapy inhibits vascular endothelial inflammation via the induction of heme oxygenase-1. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):739-45.
Far-infrared radiation promotes angiogenesis in human microvascular endothelial cells via extracellular signal-regulated kinase activation. Photochem Photobiol. 2011 Mar-Apr;87(2):441-6.
Far infra-red therapy promotes ischemia-induced angiogenesis in diabetic mice and restores high glucose-suppressed endothelial progenitor cell functions. Cardiovasc Diabetol. 2012 Aug 15;11:99.
Postconditioning with far-infrared irradiation increases heme oxygenase-1 expression andprotects against ischemia/reperfusion injury in rat testis. Life Sci. 2013 Jan 17;92(1):35-41.